Purpose
Prism has been used as a non-surgical treatment for certain types of strabismus; however, its role as the primary intervention for amblyopia combined with esotropia has been rarely studied. The objective of this study was to compare the effectiveness of prismatic correction with traditional occlusion therapy in treating amblyopia combined with esotropia.
Methods
This retrospective case-control study included children aged 3 to 16 years with amblyopia combined with esotropia. After refractive correction, the patients were divided into two groups. The control group received traditional occlusion therapy combined with binocular treatment, while the prism group received full correct prisms combined with binocular treatment. Clinical characteristics were assessed at each follow-up examination. The treatment outcomes after 12 months were evaluated to determine the more effective protocol.
Results
At baseline, there were no significant differences in clinical characteristics between the two groups (all P > 0.05). After treatment, both groups showed improvement in amblyopic eye visual acuity. The difference in visual acuity improvement between the two groups was not statistically significant at 6 months (0.18±0.17 vs 0.14±0.11, P > 0.05), but it was statistically significant at 12 months (0.35±0.20 vs 0.25±0.18, P < 0.05). The prism group demonstrated a significant improvement in binocular vision function, whereas there was no significant change in the control group at 6 months or 12 months after treatment.
Conclusion
Prismatic treatment combined with binocular treatment was more effective in improving amblyopic eye visual acuity and binocular vision compared to traditional occlusion therapy combined with binocular treatment in children with amblyopia combined with esotropia. Prismatic correction could be considered as the first-line treatment for amblyopia combined with esotropia.