Session: Poster session C
Prevalence of strabismus after 12 years of treatment of type 1 prethreshold retinopathy of prematurity (ROP) in Southeast Bulgaria
INTRODUCTION: To present the prevalence of strabismus in prematures, treated for type 1 prethreshold ROP after 12 years of follow up in Southeast Bulgaria.
METHODS: Since year 2010, 164 prematurely born children (319 eyes) were treated for type 1 prethreshold ROP and were prospectively followed up. Mean (range) gestational age was 28.6 (23 – 33) wg, and mean (range) birth weight – 1143 (570 – 1990) grams. Cryotherapy was applied on 76 eyes (23.2%), laser – in 215 eyes (65.5%), anti-VEGF – in 10 eyes (3%) and surgery – in 18 eyes (5.5%). Ten children (20 eyes - 6.1%) were lost to follow up. Presence of strabismus was checked in all 164 children aged from 1 to 12 years using Hirschberg test. Confidence intervals (95%) were calculated using the binominal distribution.
RESULTS: Among the 164 examined children 36 showed strabismus (22.0%, 95% confidence interval: 15.9% - 29.1%). Twenty-six of them (72.2%, 95% confidence interval: 54.8% - 85.8%) had strabismus and favorable structural retinal outcome. Ten children had unfavorable structural outcome (7 children with one eye total retinal detachment; 1 child with both eyes total retinal detachment and 2 children with partial retinal detachment).
CONCLUSION: The results of our study confirm the increased prevalence of strabismus in prematurely born children, treated for ROP even with favorable structural outcome. This means that these patients should be carefully followed up at shorter intervals, compared to full term born children.
KEY WORDS: ROP, treatment, strabismus
METHODS: Since year 2010, 164 prematurely born children (319 eyes) were treated for type 1 prethreshold ROP and were prospectively followed up. Mean (range) gestational age was 28.6 (23 – 33) wg, and mean (range) birth weight – 1143 (570 – 1990) grams. Cryotherapy was applied on 76 eyes (23.2%), laser – in 215 eyes (65.5%), anti-VEGF – in 10 eyes (3%) and surgery – in 18 eyes (5.5%). Ten children (20 eyes - 6.1%) were lost to follow up. Presence of strabismus was checked in all 164 children aged from 1 to 12 years using Hirschberg test. Confidence intervals (95%) were calculated using the binominal distribution.
RESULTS: Among the 164 examined children 36 showed strabismus (22.0%, 95% confidence interval: 15.9% - 29.1%). Twenty-six of them (72.2%, 95% confidence interval: 54.8% - 85.8%) had strabismus and favorable structural retinal outcome. Ten children had unfavorable structural outcome (7 children with one eye total retinal detachment; 1 child with both eyes total retinal detachment and 2 children with partial retinal detachment).
CONCLUSION: The results of our study confirm the increased prevalence of strabismus in prematurely born children, treated for ROP even with favorable structural outcome. This means that these patients should be carefully followed up at shorter intervals, compared to full term born children.
KEY WORDS: ROP, treatment, strabismus